deacetylation相关论文
HDAC5 mediated deacetylation and nuclear localization of SOX9 is critical for tamoxifen-resistance i
Objective Although endocrine therapy using estrogen antagonist tamoxifen can effectively improve the survival rate of es......
Vascular hyporeactivity is one of the major causes responsible for refractory hypotension and associated mortality in va......
The Chinese Society of Biochemistry and Molecular Biology.(Main text of Abstract;Times New Roman,12 points,1.5 line spac......
SIRT1, a highly conserved NAD+-dependent protein deacetylase, plays a pivotal role in thepathogenesis and therapy of ath......
Methyltransferase Dnmt3a Upregulates HDAC9 to Deacetylate TBK1 for Activation of Antiviral Innate Im
Epigenetic regulation of innate immunity needs further identification.Dnmt3a,a de novo DNA methyltransferase,is highly e......
目的:评价烟酰胺腺嘌呤二核苷酸(NADn +)介导的沉默信息调节因子1(SIRT1)去乙酰化活性在小鼠内毒素性急性肺损伤(ALI)中的作......
A domesticated Harbinger transposase forms a complex with HDA6 and promotes histone H3 deacetylation
In eukaryotes,histone acetylation is a major modification on histone N-terminal tails that is tightly connected to trans......
Selective and facile deacetylation of pentacyclic triterpenoid under methanolic ammonia condition an
The acetyl ester plays an important role for protection of the hydroxyl groups in carbohydrates synthesis. In the presen......
A domesticated Harbinger transposase forms a complex with HDA6 and promotes histone H3 deacetylation
In eukaryotes, histone acetylation is a major modification on histone N-terminal tails that is tightly connected to tran......
Ischemic stroke is the second leading cause of death worldwide with limited medications and neuroinflammation was recogn......
TANK-binding kinase 1 (TBK1),a core kinase of antiviral pathways,activates the production of interferons (IFNs).It has b......
Sirtuin 6(SIRT6),a member of the sirtuin family,is a nicotinamide adenine dinucleotide(NAD+)-dependent deacetylase that ......
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,A SIRT4-like auto ADP-ribosyltransferase is essential for the environmental growth of Mycobacterium
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Nε-lysine acetylation is one of the most abundant post-translational modifications in eukaryote and prokaryote.Protein ......
The p53 tumor suppressor is a sequence-specific transcription factor that undergoes an abundance of post-translational m......
Deacetylation of TFEB promotes fibrillar degradation by upregulating lysosomal biogenesis in microgl
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Detection of serum tumor marker contents of liver cancer patients and itscorrelation with JAK-STAT p
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
A highly regioselective O-deacetylation of taxanes at C-5 position was accomplished by treatment with t-BuOK and a possi......
This paper presents experimental results on the effect of alkalis such as NaOH, KOH and Ca(OH)2 on deacetylation of a ko......
氧化应激损伤是指人体处于氧化应激环境下,体内产生活性氧自由基超过氧化抗氧化系统平衡,导致人体的损伤。沉默信息调节因子1(SIRT......
对微波法制取蚕蛹壳聚糖的工艺条件进行了研究。通过单因素试验考察了NaOH质量分数、微波功率、处理时间以及甲壳素与NaOH溶液的配......
研究了甲壳质分步脱乙酰制壳聚糖反应的温度、时间、NaOH含量和预浸泡时间对脱乙酰度的影响。结果表明，最佳的反应温度为110℃，反应......
研究了用微波加热（２４５０ＭＨｚ７００ｗ）将甲壳素与４５％ＮａＯＨ溶液进行反应，此法比常规水浴加热法较大地缩短了碱处理时间，制备的壳聚春脱乙酰化度、糖度均较常规水浴......
利用酶与酸碱相结合,从废弃虾蟹壳中提取几丁聚糖,与传统方法相比,具有降低成本,减少污染等优点;通过SAS系统软件得到最佳工艺参数......
本工作制备了具有不同胺基含量的系列壳聚糖样品,测定和研究了它们的脱乙酰度(D.D.)和溶液拆光指数增量(dn/dc)。发现不同D.D.壳聚......
近几年来甲壳后，壳聚糖在医药，环保，纺织，印染，造纸等领域中得到了广泛的应用，甲壳质脱乙酰度的高低直接影响到壳聚糖的性质，因此，壳聚糖所......
本文研究了甲壳素品种、质量、粒度、碱处理方式、保护气体、干燥条件等因素对壳聚糖质量的影响.......
Trans-(-)-ε-viniferin(ε-viniferin)has antioxidative and anti-inflammatory effects.It also has neuroprotective effects ......
AIM To investigate the potential effect of curcumin on hepatitis B virus(HBV) covalently closed circular DNA(ccc DNA) an......
分别以８种一元醇和水做溶剂，配制成不同ＮａＯＨ浓度及醇水比的溶液，在此溶液中进行了甲壳质脱乙酰反应。发现，不同醇、氢氧化钠浓度、醇水比、......
沉默信息调节因子1（SIRT1）是烟碱胺腺嘌呤二核苷酸（NAD＋）依赖的组蛋白去乙酰化酶,参与细胞衰老、凋亡、分化等生理活动。近来研究表明,S......
以壳聚糖粗品（脱乙酰度65％）为原料，在二甲亚砜-氢氧化钠体系中运用超声波技术加速脱乙酰反应，制备了脱乙酰度达97．4％的壳聚糖，研究了相转移......
组蛋白乙酰化作用是目前研究广泛的组蛋白翻译后修饰过程之一,在调节表观遗传过程中发挥重要作用。组蛋白去乙酰酶2作为Ⅰ型组蛋白......
遗传信息的传递是从核酸序列三联密码子的转录和翻译，到合成具有完整结构的功能蛋白质的全过程。随着对遗传信息库的认识越来越深入......
壳聚糖是天然聚合物甲壳素脱乙酰化产物，是一种具有重要开发研究价值的天然生物多糖资源，这里主要介绍了壳聚糖及其作为吸附剂、絮凝......
比较了微波场中密闭式及开放式条件下，甲壳素非均相碱法脱乙酰反应的动力学情况。研究表明：在密闭条件下，温度为120℃时，1．5min～24min内，......
研究了KCl浓度对几丁质在微波场中脱乙酰反应的影响. 结果表明,引入盐离子促进了反应的进行. 随着反应时间的延长,几丁聚糖的脱乙......
<正> 近年来,从甲壳素(聚[(1,4)-2-乙酰胺基-2-脱氧-β-D-葡萄糖])制备壳聚糖的研究和生产以及对其理论和应用的探索,越来越广泛和......
对目前测定壳聚糖脱乙酰度（DD）的几种常用的方法进行了实际操作，对于不同的方法，总结出了其相对的优缺点。酸碱滴定法，是比较传统的检测......
Chitosan synthesized locally with a degree of deacetylation 71% and chitosan with a degree of deacetylation 68% from Sig......
Biocatalytic production of chitosan polymers from shrimp shells, using a recombinant enzyme produced
Chitosan has a unique chemical structure with high charge density, reactive hydroxyl and amino groups, and extensive hyd......
为了获得蘑菇中甲壳素脱乙酰化度高的中分子量壳聚糖，采用微波法对蘑菇中提取的甲壳素脱乙酰化工艺进行了优化。结果表明；在NaOH质量......
甲壳素是一种天然高分子物质，由于甲壳素分子链是以束状微晶形式存在且分子间有强烈的氢键，使得它的化学反应性很低。本文报导了在微......
组蛋白去乙酰化酶是一类调节组蛋白和非组蛋白赖氨酸残基去乙酰化的酶,与转录调控、细胞周期、蛋白转运和血管发生等密切相关。精......
以乙醇为反应介质，采用溶解深沉法制备了高脱乙酰壳聚糖。在反应温度８０℃，反应时间３ｈ，壳聚糖与氢氧化钠和乙醇的质量比为１：３：１６的条件下，获得了脱......
密闭条件下微波场中研究反应条件对甲壳素脱乙酰反应的影响.结果表明:120℃时,反应18min,脱乙酰度已超过90%,特性黏度达到440mL/g......
